This fascinating saga of four generations spanning 100 years and narrated by the town historian centers on the families living in a small Southern town. Although this seems like the typical community, dark factors are at play. Crimson and Scarlet delves into the unknown facts that have shaped the families living in the fictional town of Southside. Michael Browning, a young minister, is pursuing Charlotte Cote, a bad girl turned evangelist. However, there is trouble in their relationship. While there is love in Southside, there is also greed, drug dealing, larceny, and even murder. The idiosyncrasies and weaknesses planted in each family have taken root as generational curses that culminate in crisis. Is the town indeed cursed, or can it overcome the sins of the past to be reborn?